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Table 2 IL-4RA and IL-13 polymorphisms in children with Alternaria -sensitive moderate-severe asthma compared to Alternaria -sensitive mild asthma.

From: Association of IL-4RA single nucleotide polymorphisms, HLA-DR and HLA-DQ in children with Alternaria-sensitive moderate-severe asthma

Study Moderate-Severe
(60)
Mild
(49)
P
IL-4RA SNPs    
   ile75val 83 (0.627) 57 (0.388) 0.005 (0.012)
   glu400ala 61 (0.390) 49 (0.265)  
   cys431arg 15 (0.102) 22 (0.112)  
   ser503pro 53 (0.347) 37 (0.214)  
   gln576arg 75 (0.534) 59 (0.406)  
IL-13 SNP    
   arg110gln 31 (0.178) 37 (0.204)  
75val/576arg 63 38 0.012
75val/110gln 31 17  
75val/576arg/110gln 22 8 0.07
  1. Abbreviations: IL-4RA, IL-4 receptor alpha chain; SNP single nucleotide polymorphisms.
  2. Data presented as percentage (%) of patients and in parentheses, allele frequency.
  3. P value using Fisher's exact test.