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Table 3 Genotype distributions and allele frequencies for 314C/T polymorphism of HNMT gene from five association studies in asthma (asthmatic patients vs. control group)

From: Polymorphisms of two histamine-metabolizing enzymes genes and childhood allergic asthma: a case control study

 

Asthma (n = 1049)

Control group (n = 1242)

P value

CC

806 (76.8)

1011 (81.4)

0.007*

CT

221 (21.1)

219 (17.6)

 

TT

22 (2.1)

12 (1.0)

 

C

1833 (87.4)

2241 (90.2)

0.002*

T

265 (12.6)

243 (9.8)

 
  1. * Indicates significance: for genotypes: χ2 = 9.839, df = 2; for alleles: χ2 = 9.075, df = 1, OR = 1.33, 95%CI: 1.108-1.604.
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Clinical and Molecular Allergy

ISSN: 1476-7961

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