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Table 3 Genotype distributions and allele frequencies for 314C/T polymorphism of HNMT gene from five association studies in asthma (asthmatic patients vs. control group)

From: Polymorphisms of two histamine-metabolizing enzymes genes and childhood allergic asthma: a case control study

  Asthma (n = 1049) Control group (n = 1242) P value
CC 806 (76.8) 1011 (81.4) 0.007*
CT 221 (21.1) 219 (17.6)  
TT 22 (2.1) 12 (1.0)  
C 1833 (87.4) 2241 (90.2) 0.002*
T 265 (12.6) 243 (9.8)  
  1. * Indicates significance: for genotypes: χ2 = 9.839, df = 2; for alleles: χ2 = 9.075, df = 1, OR = 1.33, 95%CI: 1.108-1.604.