Figure 1

The fold change values of plasma inflammatory molecules and eosinophil counts. On Feb. 2, the eosinophil count (Eosino #) was already high (17.6 fold) and became the highest (35.5 fold) on Feb. 13 followed by a decrease after the cessation of insulin aspart & insulin aspart 30 mix on Feb. 13. OPN and sIL-2R were already elevated 1.7 fold and 4.7 fold, respectively on Feb. 2, but GAL-9 was elevated 22.5 fold more than the cut-off point. The elevations of OPN and sIL-2R were not changed on Feb. 16 but that of GAL-9 started to decrease. OPN and sIL-2R titers were still 1.4 and 2.7 fold higher on Mar. 9, but the GAL-9 level became normal.