Table 3 Family-based Analysis of Association between IL12A and Cockroach Sensitization among Children with Asthma in Costa Rica and White Children with Asthma in CAMP
From: Polymorphisms in IL12A and cockroach allergy in children with asthma
Costa Ricans | CAMP | ||||||||
|---|---|---|---|---|---|---|---|---|---|
SNP (dbSNP number) | Chromosome 3 position | Alleles | Location | N* | Model | FBAT P value | N* | Model | FBAT P value |
Positive IgE to B. germanica | |||||||||
rs2243123 | 161192344 | T>C | Intron | 245 | a | +0.046 | |||
rs2243151 | 161198714 | A>T | 3'UTR | 277 | a | 0.05 | |||
133 | r | +0.04 | |||||||
STR to P. Americana | |||||||||
rs2243123 | 161192344 | T>C | Intron | 244 | a | +0.03 | 301 | a | - |
84 | r | +0.002 | 94 | r | - | ||||
rs2243151 | 161198714 | A>T | 3'UTR | 276 | a | +0.03 | 335 | a | - |
133 | r | +0.01 | 169 | r | - | ||||
rs17826053 | 161200322 | T>G | 3'UTR | 120 | a | - | 203 | a | +0.02 |
119 | r | - | 198 | r | +0.01 | ||||
STR to B. germanica | |||||||||
rs2243123 | 161192344 | T>C | Intron | 244 | a | - | 301 | a | - |
84 | r | +0.01 | 94 | r | 0.09 | ||||
rs2243151 | 161198714 | A>T | 3'UTR | 276 | a | 0.08 | 335 | a | 0.09 |
133 | r | +0.0007 | 169 | r | -0.03 | ||||
rs17826053 | 161200322 | T>G | 3'UTR | 120 | a | - | 203 | a | +0.004 |
119 | r | - | 198 | r | +0.007 | ||||