Figure 4From: Severe asthma and the omalizumab optionAdministration of Epipen auto–injector. Panel 1 shows an auto–injector, and panels 2–4 demonstrate steps in arming the autoinjector and self-administration technique. The patient should grip the unit with the black tip pointing downward (panel 2) and proceed to pull off the gray safety release (panel 3). The injector should then be applied at a 90° angle with the outer thigh and held firmly for approximately 10 seconds after a click is heard (panel 4).Back to article page