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Table 6 Mean adjusted1) total serum IgE levels in cases and non-atopic controls2) in dependence of IL6(-174G>C) or IL18(-137G>C) genotype in the SAPALDIA Cohort Study.

From: Cytokine gene polymorphisms and atopic disease in two European cohorts. (ECRHS-Basel and SAPALDIA)

  

Hay fever3)

Controls2)

Genotype

 

Number

Mean 4)

P-value

Number

Mean 4)

P-value

IL6 (-174G>C)

GG

347

83.56

 

986

25.49

 
 

GC

483

61.29

 

1255

22.35

 
 

CC

148

62.26

0.009

412

23.29

0.11

IL18 (-137G>C)

GG

494

71.85

 

1464

23.79

 
 

GC

419

60.73

 

997

23.21

 
 

CC

71

103.20

0.01

196

24.96

0.80

  1. 1) Adjusted for age and gender. 2) Non-atopic controls were free of self-reported hay fever, self-reported eczema and physician-diagnosed asthma. 3) Self-reported hay fever cases answered yes to 'Have you ever had a problem with sneezing or a runny nose or a blocked nose when you did not have a cold?', irrespective of self-reported asthma or eczema. 4) Measured total serum IgE levels were log-transformed and adjusted means are geometric means.