From: Cytokine gene polymorphisms and atopic disease in two European cohorts. (ECRHS-Basel and SAPALDIA)
 |  | Hay fever3) | Controls2) | ||||
---|---|---|---|---|---|---|---|
Genotype | Â | Number | Mean 4) | P-value | Number | Mean 4) | P-value |
IL6 (-174G>C) | GG | 347 | 83.56 | Â | 986 | 25.49 | Â |
 | GC | 483 | 61.29 |  | 1255 | 22.35 |  |
 | CC | 148 | 62.26 | 0.009 | 412 | 23.29 | 0.11 |
IL18 (-137G>C) | GG | 494 | 71.85 | Â | 1464 | 23.79 | Â |
 | GC | 419 | 60.73 |  | 997 | 23.21 |  |
 | CC | 71 | 103.20 | 0.01 | 196 | 24.96 | 0.80 |