Intestinal strongyloidiasis and hyperinfection syndrome

Table 2 Clinical Manifestations of Strongyloidiasis by Organ System

Organ System	Symptoms	Signs	Investigation	References
Skin	Pruritis, Eruption	Urticaria, Angioedema, Larva Currens, Eruption	CBC with differential counts
GI	Abdominal pain, Diarrhea, Nausea, Vomiting	Weight loss, Malabsorption, Epigastric tenderness	Stools for parasites, Strongyloid antibody titer	[1]
Pulmonary	Wheezing, Cough, Hemoptysis, Shortness of breath	Wheeze, Rales	Chest X ray, Sputum culture, Sputum for parasites
CNS	Headache, Altered mental state, Focal seizures, Coma	Meningeal signs, Disorientation	Lumbar puncture and cultures	[1]
Immune/Allergic	Urticaria, Anaphylaxis	Urticarial rash, Larva Currens rash	CBC with differential counts	[65]
Hematological	Fever, Chills, Rigors	Tachycardia, Bacteremia, Septicemia, Eosinophilia	Blood cultures, CBC with differential counts	[1]
Other (Rare)	Peritonitis, Endocarditis, Eosinophilic pleural effusion, Eosinophilic granulomatous enterocolitis			[1] [39] [40]

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