Table 2 IL-4Rα single nucleotide polymorphisms in asthmatic and cystic fibrosis patients with allergic bronchopulmonary aspergillosis (ABPA).
From: IL-4 alpha chain receptor (IL-4Rα) polymorphisms in allergic bronchopulmonary sspergillosis
Study | Number of Patients | P* | |
|---|---|---|---|
ABPA (40) | Non-ABPA (56) | ||
Extracellular IL-4Rα SNPs | |||
ile75val | 32 (80%) | 30 (54%) | 0.008 |
asn98thr | 2 (5%) | 4 (8%) | ns |
Homozygous ile75val | 17 (43%) | 6 (11%) | 0.0003 |
Cytoplasmic IL-4Rα SNPs | |||
glu400ala | 5 (13%) | 3 (5%) | ns |
cys431arg | 3 (8%) | 4 (7%) | ns |
ser503pro | 9 (23%) | 10 (18%) | ns |
gln576arg | 8 (20%) | 14 (25%) | ns |
Any IL-4Rα SNP | 38 (95%) | 34 (61%) | 0.0001 |
Extracellular and Cytoplasmic IL-4Rα SNP | 11 (28%) | 12 (21%) | ns |