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Table 2 Genotype distribution and p-values for association

From: Impact of IL8 and IL8-Receptor alpha polymorphisms on the genetics of bronchial asthma and severe RSV infections

Polymorphism

Genotype distribution

p-values for association

 

Asthma

RSV

Controls

Asthma- Controls

RSV- Controls

Asthma- RSV

IL8 rs4073 (-251A/T)

64; 148; 101

26; 73; 34

70; 124; 74

0.087

0.550

0.425

IL8 rs2227306 (-781C/T)

123; 147; 48

37; 62; 27

84; 124; 61

0.011

0.937

0.034

IL8RA rs16858811 (M31R)

299; 20; 0

128; 7; 0

245; 25; 0

0.174

0.152

0.655

IL8RA rs16858809 (S276T)

239; 30; 0

121; 14; 0

121; 14;0

0.409

0.812

0.376

IL8RA rs16858808 (R335C)

298; 21; 0

127; 7; 0

246; 23; 1

0.239

0.171

0.584

  1. The genotype distribution within the three different populations is given in the following order: homozygous wildtype, heterozygous and homozygous mutation. Also listed are the p-values for association with the diseases as calculated by the Armitage's trend test.
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Clinical and Molecular Allergy

ISSN: 1476-7961

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