Interleukin-4 (IL4) and Interleukin-4 receptor (IL4RA) polymorphisms in asthma: a case control study

Table 2 Genotype and allele frequencies of -33C>TIL4 and 576Q>RIL4RA SNPs

Phenotype			Genotype			Allele		HWE p value
-33C>T IL4	N	Log IgE ± SD	CC	TC	TT	C	T
Controls	79	1.36 ± 0.67	0.81	0.19	0	0.91	0.09	0.35
Asthma	133	2.18 ± 0.71	0.70	0.29	0.01	0.85	0.15	0.15
Allergic Asthma	99	2.42 ± 0.56	0.69	0.30	0.01	0.84	0.16	0.24
Non-allergic Asthma	34	1.59 ± 0.76	0.74	0.26	0	0.87	0.13	0.37
Intermittent Asthma	54	2.39 ± 0.60	0.79	0.19	0.02	0.89	0.11	0.65
Persistent Asthma	79	2.09 ± 0.76	0.63	0.37*	0	0.82	0.18†	0.05
576Q>R IL4RA			AA	AG	GG	A	G
Controls	79	1.36 ± 0.67	0.62	0.33	0.05	0.79	0.21	0.82
Asthma	133	2.18 ± 0.71	0.68	0.31	0.01	0.84	0.16	0.10
Allergic Asthma	99	2.42 ± 0.56	0.71	0.29	0	0.85	0.15	0.09
Non Allergic Asthma	34	1.59 ± 0.76	0.59	0.38	0.03	0.78	0.22	0.51
Intermittent asthma	54	2.39 ± 0.60	0.67	0.33	0	0.83	0.17	0.14
Persistent asthma	79	2.09 ± 0.76	0.68	0.30	0.01	0.84	0.16	0.35

ISSN: 1476-7961