Dermatology for the practicing allergist: Tinea pedis and its complications

Table 3 List of Oral Antifungal Therapies, Their Dosages, and Their Possible Side Effects

DRUG	DOSE	SIDE EFFECTS
1. Griseofulvin*	375–500 mg qd 3–6 months	Nausea, Hepatotoxic, Photosensitivity, Headache, Leukopenia⁺, Neutropenia⁺
2. Azoles
A. Ketoconazole**	200–400 mg qd 6–8 weeks	Hepatotoxic, Hepatitis Idiosyncratic rxn, Nausea, Vomiting, Diarrhea
B. Itraconazole	100 mg qd 2–4 weeks	Abdominal pain, Increased transaminases
	400 mg qd 1 week
C. Fluconazole	50 mg qd 6 weeks	Hepatotoxic⁺, Anaphylaxis
	100 mg qd 8 weeks
	150 mg q week 6 weeks
3. Allylamines
A. Terbinafine	125 mg qd 8 weeks	Headache, Rash, Cholestatic hepatitis, Blood dyscrasia Steven-Johnson Syndrome
	250 mg qd 2–6 weeks

* Contraindicated in pregnancy ** Contraindicated in nursing women, ⁺ Rare side effect

ISSN: 1476-7961