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Table 4 Increased Treg Cell Frequency is Associated with ICS Use and Not Asthma Status

From: Inhaled corticosteroid use is associated with increased circulating T regulatory cells in children with asthma

Patient Classification n %Treg cells/CD4+ cells (mean, adjusted) effect* 95%CI p-value
Children not on ICS 118 6.30 -- -- 0.005
Children treated with ICS 39 7.55 1.26 (0.40, 2.12)
No asthma 93 7.03 -- -- 0.68
Non-atopic asthma 20 7.05 0.02 (-0.80, 0.84)
Atopic asthma 44 6.69 -0.34 (-1.18, 0.50)
Interaction: P = 0.35
  1. ICS Inhaled corticosteroid, 95% CI, 95% confidence interval.
  2. *difference in LS means%Treg cells/CD4+ cells between the groups. Two asthma subjects are missing FEIA data and were excluded from the analysis.