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Table 3 Increased Treg cell frequency is associated with ICS use and not allergic sensitization

From: Inhaled corticosteroid use is associated with increased circulating T regulatory cells in children with asthma

Patient Classification n % Treg cells/CD4+ cells (mean, adjusted) effect* 95%CI p-value
Children not on ICS 116 6.38 -- -- 0.003
Children treated with ICS 39 7.32 0.94 (0.32, 1.55)
FEIA negative 71 6.76 -- -- 0.51
FEIA positive 84 6.94 0.18 (-0.35, 0.71)
Interaction: P = 0.93
  1. ICS, inhaled corticosteroid; FEIA, fluroenzyme immunoassay; 95% CI, 95% confidence interval.
  2. *difference in LS means in%Treg cells/CD4+ cells between the groups. Four children missing FEIA data were excluded from the analysis.