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Table 2 Increased Treg cell frequency is associated with ICS use and not asthma disease Severity

From: Inhaled corticosteroid use is associated with increased circulating T regulatory cells in children with asthma

Patient Classification n % Treg cells/CD4+ cells (mean, adjusted) effect* 95%CI p- value
Children not on ICS 119 6.32 -- -- 0.02
Children treated with ICS 40 7.37 1.06 (0.15, 1.96)
No asthma 93 6.93 -- -- 0.96
Intermittent 31 6.77 -0.17 (-0.91, 0.57)
Mild persistent 15 6.77 -0.17 (-1.15, 0.82)
Mod/Sev persistent 20 6.91 -0.02 (-1.17, 1.12)
Interaction: P = 0.78
  1. ICS Inhaled corticosteroid, 95% CI, 95% confidence interval.
  2. *differences in least squares (LS) means in%Treg cells/CD4+ cells between the groups.