Table 1 Patient characteristics of cow's milk allergic (CMA) children, diagnosed by food challenge (Challenge) or a convincing history of present milk allergy (History), and non-CMA children sensitized to milk.
From: The usefulness of casein-specific IgE and IgG4 antibodies in cow's milk allergic children
CMA (n = 61) | non-CMA (n = 22) | |||
|---|---|---|---|---|
Challenge | History | Tolerant | Negative | |
Sex (boys/girls) | 21/13 | 18/9 | 7/4 | 9/2 |
Age, years (median, range) | 3.9 (1.0-12.7) | 3.0 (0.8-12.8) | 2.5 (1.0-15.8) | 3.2 (1.4-14.2) |
Serology (median, range) | ||||
Total IgE (kU/L) | 395 (32.0-12,784) | 536 (34.0-14,283) | 267 (44.0-3,260) | 958 (66.1-27,815) |
Milk-sIgE (kUA/L) | 11.6 (< 0.35- > 100) | 15.9 (1.4- > 100) | 4.2 (< 0.35-27.6) | 3.9 (1.0-17.3) |
Casein-sIgE (kUA/L) | 13.0 (< 0.35- > 100) | 21.6 (0.42- > 100) | 2.3 (< 0.35-6.6) | 2.0 (1.1-4.2) |
Allergic symptoms, no (%) | ||||
Atopic dermatitis | 28 (82%) | 24 (89%) | 9 (82%) | 10 (91%) |
Asthma | 9 (26%) | 12 (44%) | 5 (45%) | 1 (9%) |
Egg allergy | 25 (74%) | 20 (74%) | 4 (36%) | 6 (54%) |
Medication, no (%) | ||||
H1-antagonist | 6 (18%) | 6 (22%) | 3 (27%) | 3 (27%) |
Inhaled corticosteroids | 2 (6%) | 5 (18%) | - | - |